Drug Discovery CROs

3 contract research organizations in our directory list at least one of In Vitro Pharmacology, In Vitro ADME, In Vivo PK, In Vivo Efficacy, Dose-Response Studies, Target Engagement, Metabolite Identification or Formulation Development, across 2 countries. 1 reports GLP capability and 2 report AAALAC accreditation. Compare their species, services and accreditations below, and contact labs directly from their profiles.

3 CROs 1 GLP 2 AAALAC 2 countries

About Drug Discovery

Drug discovery CROs help sponsors move from a target and a set of hits to a single development candidate. The biology side of that work, which is what this page covers, runs in a loop with chemistry: in vitro potency and selectivity assays rank compounds, in vitro ADME screens flag metabolic and permeability problems, and in vivo PK and efficacy studies show whether the best compounds reach their target and change disease-relevant endpoints in an animal.

Sponsors choose between integrated discovery CROs, which combine medicinal chemistry with biology, ADME and in vivo pharmacology under one project team, and specialist labs that do one part of the loop very well. Integrated providers shorten hand-offs and suit virtual biotechs without their own labs. Specialists often have deeper experience in a particular disease model, target class or species. Many programs use both. This directory lists labs by their discovery biology, ADME and in vivo capabilities; confirm chemistry capacity directly if you need it.

Whatever the model, agree on the candidate selection criteria before the work starts: the potency, selectivity, exposure and efficacy thresholds a compound must meet, plus early safety flags such as hERG and Ames results. Clear criteria keep the loop focused and make the eventual IND-enabling package faster to scope.

Preclinical outsourcing guide for biotechs →

Showing 3 CROs. Order rotates daily so no lab is permanently listed first.

NeuroBridge

CN Verified GLP AAALAC

NeuroBridge Biotechnology is a specialized preclinical research organization based in Guangzhou, China, focused on non-human primate (NHP) and pig disease models and exploratory non-GLP translational studies. We support…

In Vitro ADME In Vivo Efficacy Target Engagement AAV Biodistribution Acute Toxicity Cynomolgus monkey Minipig Non-human Primate Rhesus monkey

ANEWCRO, LLC.

US Verified

ANEWCRO is a nonclinical contract research organization (CRO) dedicated to providing innovative solutions and support to the biopharmaceutical industry, biotech startups and academic institutions. With unlimited access…

In Vivo Efficacy Catheterization CNS Drug Delivery Dose Range Finding Electroretinography (ERG) Cynomolgus monkey

Biomere

US Verified AAALAC

Biomere (a JOINN company) is a preclinical CRO based in Worcester, MA. Services include non-GLP PK/PD, discovery toxicology, surgical services, disease models, and laboratory sciences. Surgical services include…

Dose-Response Studies In Vitro Pharmacology In Vivo Efficacy In Vivo PK AAV Biodistribution Cynomolgus monkey Minipig Mouse Non-human Primate

Questions to ask when choosing a Drug Discovery CRO

  • Do you run medicinal chemistry in-house, or will discovery biology be our only interface with you?
  • How quickly can a compound move from synthesis through in vitro assays to an in vivo PK readout?
  • Which disease models have you validated for our indication, and what positive-control data can you share?
  • How is data shared during the project: a portal, regular reports, or raw data on request?
  • Who owns the assays, models and data generated during the collaboration?