DMPK and ADME CROs

1 contract research organization in our directory lists at least one of In Vivo PK, In Vitro ADME, Metabolite Identification or Toxicokinetics, based in CN. Compare their species, services and accreditations below, and contact labs directly from their profiles.

1 CRO 1 GLP 1 AAALAC 1 country

About DMPK & ADME

Drug metabolism and pharmacokinetics (DMPK) work describes how a compound is absorbed, distributed, metabolized and excreted (ADME), and how exposure changes with dose, route and species. It guides candidate selection in discovery, then supports dose and species selection for toxicology.

In vitro ADME assays such as metabolic stability, plasma protein binding, permeability and CYP inhibition screen compounds quickly and flag drug-drug interaction risk. In vivo PK studies, often in cannulated rodents and then a non-rodent species, measure exposure directly. Metabolite identification shows whether the toxicology species form the same metabolites as humans, and toxicokinetics confirms exposure within the toxicology studies themselves.

Every DMPK result depends on the bioanalytical method behind it, so ask where samples are analyzed and how methods are qualified.

ADME & pharmacokinetics guide →

Showing 1 CRO. Order rotates daily so no lab is permanently listed first.

NeuroBridge

CN Verified GLP AAALAC

NeuroBridge Biotechnology is a specialized preclinical research organization based in Guangzhou, China, focused on non-human primate (NHP) and pig disease models and exploratory non-GLP translational studies. We support…

In Vitro ADME AAV Biodistribution Acute Toxicity ADME Studies Behavioral Assessment Cynomolgus monkey Minipig Non-human Primate Rhesus monkey

Questions to ask when choosing a DMPK & ADME CRO

  • Which in vitro ADME assays do you run in-house, and with which species' matrices and hepatocytes?
  • Do you use cannulated animals for serial PK sampling, and in which species?
  • Is bioanalysis done on site, and what is the turnaround from last sample to PK report?
  • Can you compare metabolite profiles across species to support toxicology species selection?