Eurofins Advinus
Bengaluru-based preclinical CRO, part of Eurofins, offering GLP safety assessment, DMPK and discovery services for pharmaceutical and agrochemical sponsors.
About Repeat-Dose Toxicity
Repeat-dose toxicity studies characterize the effects of daily or periodic dosing over weeks to months, and their duration determines how long a clinical trial can dose (ICH M3(R2)). Most programs need one rodent and one non-rodent species, often with recovery groups and toxicokinetics.
Repeat-Dose Toxicity CROs
Showing 12 CROs. Order rotates daily so no lab is permanently listed first.
LPT Laboratory of Pharmacology and Toxicology
Independent German preclinical CRO conducting GLP toxicology, reproductive toxicology, carcinogenicity and safety pharmacology studies across rodent and non-rodent species.
Shin Nippon Biomedical Laboratories (SNBL)
Long-established Japanese CRO with large GLP nonclinical safety facilities and deep nonhuman primate experience, supporting toxicology, safety pharmacology and pharmacokinetics.
Biotoxtech
Korean non-clinical CRO offering IND and NDA-enabling GLP toxicology, including general, reproductive and genetic toxicity, carcinogenicity and safety pharmacology, with NHP capacity through its group companies.
Korea Institute of Toxicology (KIT)
Government-funded Korean research institute providing GLP nonclinical safety studies, including inhalation toxicology, safety pharmacology and reproductive toxicity.
K-Prime Research (BTT Group)
Korean nonhuman primate CRO in the Biotoxtech group with GLP repeat-dose toxicity and cardiovascular safety pharmacology in NHPs, plus NHP inhalation studies.
Jai Research Foundation (JRF)
Indian GLP CRO providing regulatory toxicology and safety studies for pharmaceuticals, agrochemicals, chemicals and biologics.
Scantox
GLP-accredited preclinical CRO headquartered in Denmark with sites in Sweden, Austria and the UK. Known for Gottingen minipig work and regulatory toxicology, with discovery pharmacology including CNS and…
CorestemChemon (ChemOn)
South Korea's first private non-clinical CRO, providing GLP toxicity, safety pharmacology, pharmacokinetic and efficacy studies for drugs, chemicals and biologics.
Research Toxicology Centre (RTC)
Italian GLP CRO near Rome providing regulatory toxicology and safety studies for pharmaceuticals, chemicals and agrochemicals.
Sequani
Independent UK preclinical CRO offering GLP general, reproductive and juvenile toxicology studies for pharmaceutical and biotech sponsors.
Accelera
Non-clinical CRO near Milan and part of the NMS Group, offering GLP safety assessment and toxicology, safety pharmacology and preclinical regulatory consulting to move candidates toward IND/CTA.
Questions to ask when choosing a Repeat-Dose Toxicity CRO
- Can you run the rodent and non-rodent arms in parallel to shorten the timeline?
- How are toxicokinetic samples collected and where is bioanalysis done?
- What historical control data do you hold for this species and strain?